热烈祝贺上海信帆生物销售的elisa试剂盒被国外SCI收录

热烈祝贺我司客户又一篇SCI文章被知名期刊收录

祝贺我司客户的研究成果被知名期刊《Clinical Rheumatology》收录

该论文标题： Predictors of response to TNFα antagonist therapy in Chinese rheumatoid arthritis
Clinical Rheumatology

发表日期：July 2015, Volume 34

期刊号：Issue 7, pp 1203–1210

老师在论文后期编辑过程中与我们积极互动，信帆生物给予了支持，终顺利被《Clinical Rheumatology》录用。

该论文中所使用的以下ELISA试剂盒均购自我司。

Human IL-34 ELISA KIT(Xinfan Biotechology Co.,Ltd,shanghai，China)

Human TNF-a  ELISA KIT(Xinfan Biotechology Co.,Ltd,shanghai，China)

Human IL-6 ELISA KIT(Xinfan Biotechology Co.,Ltd,shanghai，China)

Human IL-8 ELISA KIT(Xinfan Biotechology Co.,Ltd,shanghai，China)

Human MMP-3  ELISA KIT(Xinfan Biotechology Co.,Ltd,shanghai，China)

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热烈祝贺上海信帆客户又一篇SCI文章被知名期刊收录
《Clinical Rheumatology》期刊介绍：
Clinical Rheumatology is an international journal devoted to publishing in the English language original clinical investigation ａnd research in the general field of rheumatology with accent on clinical aspects at postgraduate level. Studies carried out anywhere in the world will be considered the basic criterion for acceptance being the medical ａnd scientific standard of the work described.

文章介绍

This study aimed to investigate the clinical, immunological, ａnd radiologic predictors of response to tumor necrosis factor (TNF)-α antagonist therapy in Chinese rheumatoid arthritis (RA). Ninety RA patients were divided into two groups according to their responsiveness to TNF-α antagonist therapy at 1 month: group A (responders) ａnd group B (non-responders). After 3 months of therapy, all the 90 patients were re-assessed ａnd re-divided into another two groups: group C (responders) ａnd group D (non-responders). Serum samples ａnd clinical characteristics as well as radiographic features were collected at baseline, first month, ａnd third month post-initial administration of TNF-α antagonist. Serum TNF-α, interleukin (IL)-6, IL-8, IL-34, ａnd matrix metalloproteinase (MMP)-3 were measured by enzyme-linked immunosorbent assay (ELISA). Disease activity ａnd Sharp score were evaluated. (1) Comparisons between groups A ａnd B: subjects in group A showed a lower level of erythrocyte sedimentation rate (ESR) ａnd a higher level of albumin (ALB) at baseline than that of group B (p < 0.05). The cutoff value of ALB for prediction was ≥34.9 g/l ａnd that of ESR was ≤55.5 mm/h. (2) Comparisons between groups C ａnd D: group C showed lower levels of ESR, health assessment questionnaire (HAQ), ａnd IL-34 at baseline (p < 0.05). The threshold for prediction were as follows: ESR ≤60 mm/h, HAQ ≤1.3125, ａnd IL-34 ≤194.12 pg/ml. (3) The serum cytokines were positively correlated with C-reactive protein (CRP) ａnd disease activity index, while ALB was negatively correlated with CRP ａnd disease activity. Baseline ALB ≥34.9 g/l or ESR ≤55.5 mm/h might predict a good response at 1-month treatment of TNF-α antagonist, while baseline ESR ≤60 mm/h, HAQ ≤1.3125, ａnd IL-34 ≤194.12 pg/ml might predict a good response at 3-month treatment.

热烈祝贺上海信帆生物销售的ELISA试剂盒被国外SCI收录